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A drug company maintains that a new drug G for a certain disease has a 50% cure rate as compared


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The Question

A drug company maintains that a new drug G for a certain disease has a 50% cure rate as compared with drug H, which has only a 25% cure rate. You are asked to design a clinical trial comparing drugs G and H. Using the table, estimate the number of patients needed in each therapy group to detect such a difference with alpha = .05, two-sided and beta = .20.The number of patients needed in each therapy group is:

Number of Patients Needed in an experimental and a control Group for a Given probability of Obtaining a Significant Result (Two-sided Test)

DIFFERENCES IN THE CURE RATES BETWEEN THE TWO TREATMENT GROUPS

Lower of the Two Cure Rates

.05

.10

.15

.20

.25

.30

.05

.10

.15

.20

.25

.30

.35

.40

420

680

910

1,090

1,250

1,380

1,470

1,530

130

195

250

290

330

360

370

390

69

96

120

135

150

160

170

175

44

59

71

80

88

93

96

97

36

41

48

53

57

60

61

61

31

35

39

42

44

44

44

44

Alpha = .05; power (1 ? beta) = .80

 


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Solution #00070113

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A drug company maintains that a new drug G for a certain disease has a 50% cure rate as compared .zip

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This paper was answered on 14-Oct-2020

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