A drug company maintains that a new drug G for a certain disease has a 50% cure rate as compared with drug H, which has only a 25% cure rate. You are asked to design a clinical trial comparing drugs G and H. Using the table, estimate the number of patients needed in each therapy group to detect such a difference with alpha = .05, two-sided and beta = .20.The number of patients needed in each therapy group is:
Number of Patients Needed in an experimental and a control Group for a Given probability of Obtaining a Significant Result (Two-sided Test)
DIFFERENCES IN THE CURE RATES BETWEEN THE TWO TREATMENT GROUPS
Lower of the Two Cure Rates
Alpha = .05; power (1 ? beta) = .80
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Oct 14, 2020EXPERT
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