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Alzheimer's Disease Research Paper...
Please conduct a review of the epidemiological data and scholarly literature regarding your chosen topic; at least10 reliable sources, including at least 6 academic/peer-reviewed journal articles. Your overall goal is to analyze and synthesize information about your topic with an emphasis on health disparities, health equality and a life course (or lifespan) perspective, including information about prevalence, risk and protective factors. Also, you are required to review and critique at least one existing public health program and/or policy regarding your topic, and include your recommendations for the future. Each paper should contain the following:? A key research question or thesis statement for the over-arching focus.? An introduction that clearly describes the relevance of the topic to health and wellness
across the life course.? At least 5 key dimensions of the topic area that is being considered. For example:Prevalence of issue, risk and protective factors, health disparities, health equity, and public health program(s) (or policy).? A conclusion section that ties together the key themes and discusses practice/policy implications and your recommendations.? Each dimension explored (or each section of the paper) should include at least 3 different references in order to demonstrate integration and synthesis of ideas.Your paper should be 10-15 pages in length (12-point font, double-spaced, APA formatting), in addition to a cover page and bibliography. The Online Writing Lab at Purdue University (OWL)has an online guide that explains proper APA citation for all sources. It also offers some helpful information about how to write a research paper. Link to the OWL:https://owl.english.purdue.edu/owl/resource/658/02/
- Attached are more detailed instruction, grading rubric, sources*
- Please use the 10 sources I have provided and add more if necessary.*
Hershey 1 Annotated Bibliography
Barnes, D. E., & Yaffe, K. (2011). The projected effect of risk factor reduction on Alzheimer's
Disease prevalence. The Lancet Neurology, 10(9), 819-828. doi:10.1016/s14744422(11)70072-2
In this journal article Dr. Barnes and Prof Yaffe explore the projected effect of risk factor
reduction on Alzheimer?s disease. The aim of the review was to summarize the evidence
regarding seven potential modifiable risk factors for Alzheimer?s disease. These common
risk factors were diabetes, hypertension, obesity, smoking, depression, cognitive
inactivity, and physical activity. After, calculating population attribute risks and the
number of AD cases that might be prevented by risk factor reduction, the researchers
found that up to half of AD cases worldwide are potentially caused by these modifiable
risk factors. They agree at the end that more public health campaigns targeted at AD risk
factor modification should be developed and implemented.
As an experienced academic pair, Dr. Barnes and Prof Yaffe were aware of previous
general background literature and statics regarding Alzheimer?s disease on an
international level. They supported their ideas that there?re concrete risk factors, which
greatly influence the development of the disease with search strategy and selection
criteria methods. The academic journal article is timely, reliable, descriptive, well
researched, and peer-reviewed.
The annotation above both summarizes and assesses the scientific journal article in the
citation. The first paragraph provides a brief summary of the researchers objectives,
pertinent background knowledge, and a summary covering the main points of their work.
The second paragraph points out the projects strengths and evaluates its methods and
presentation. This particular annotation reflects the source?s importance as a resource
filled with detailed statics discussing the effect of risk factors on Alzheimer?s disease
prevalence. This source has changed the way I perceive the worldwide scale and
prevalence of the disease.
Brookmeyer, R., Evans, D. A., Hebert, L., Langa, K. M., Heeringa, S. G., Plassman, B. L., &
Kukull, W. A. (2011, January 01). National estimates of the prevalence of Alzheimer?s
Disease in the United States. Alzheimer's & Dementia, 7(1), 61-73.
doi:10.1016/j.jalz.2010.11.007
In this journal article Jack C de la Torre form the Center for Alzheimer?s Research in
Arizona, discusses the major cardiovascular risk factors associated with Alzheimer?s
disease and how to lessen the catastrophic impact on future US healthcare. The
researchers believe some individuals with even very mild memory complaints should Hershey 2 undergo screening using echocardiography and ultrasound. These non-invasive, safe,
cost-effective ultrasound techniques can often detect correctable or treatable early lesions
involving the heart, which can be a trigger of AD. They firmly believe this clinical
approach may have an important impact in reducing the number of new AD cases in the
US. The aim of this review is to try and prevent, reverse or at least delay, the onset of
clinically significant dementia symptoms.
As an experienced researcher, Jack C de la Torre is well learned of current and dated
prevalence epidemiologic studies of AD. Their claims that poor cardiovascular health is a
major trigger of AD are well supported. Previous scholarly research, and epidemiological
data on AD and cardiovascular disease were used to back up their arguments. The
academic journal article is timely, reliable, descriptive, well researched, peer-reviewed
and there are no conflicts of interest.
The annotation above both summarizes and assesses the scientific journal article in the
citation. The first paragraph provides a brief summary of the researchers objectives,
pertinent background knowledge, and a summary covering the main points of their work.
The second paragraph points out the projects strengths and evaluates its methods and
presentation. This particular annotation reflects the article?s importance as a source for an
Alzheimer?s research paper.
Gilligan, A. M., Malone, D. C., Warholak, T. L., & Armstrong, E. P. (2012, November 29).
Health Disparities in Cost of Care in Patients With Alzheimer's Disease: An Analysis
Across 4 State Medicaid Populations. American Journal of Alzheimer's Disease and
Other Dementias, 28(1), 84-92. doi:10.1177/1533317512467679
In this journal article the authors investigate health disparities with respect to cost of care
across 4 state Medicaid populations. The researchers outlined the statics of the disease,
and then examined the issue of racial/ethnic disparities in Alzheimer?s patients and cost
of care rates. Patients were enrolled in a California, Florida, New Jersey, or New York
Medicaid programs during 2004, with a diagnosis of Alzheimer?s disease. They found the
largest disparities were found between blacks and whites in cost of care. The conclusions
were that disparities in cost among minority-to-minority populations were just as
prevalent, if not higher, than minority?white disparities. They also, identified the
significant drivers of health disparities across the racial groups. They admitted future
research should examine these relationships more closely.
As an experienced research team, Gilligan, Malone, Warholak, and Armstrong are aware
of the general background literature regarding Alzheimer?s disease. They supported their
ideas that there are huge racial/ethnic dipartites related to the disease. Scholarly research,
and data collection was used successfully to back up the teams arguments. There was a
declaration of conflicting interests stating, the authors received no finical support for their Hershey 3 funding. The academic journal article is timely, reliable, descriptive, well researched, and
peer-reviewed.
The annotation above both summarizes and assesses the scientific journal article in the
citation. The first paragraph provides a brief summary of the researchers objectives,
pertinent background knowledge, and a summary covering the main points of their work.
The second paragraph points out the projects strengths and evaluates its methods and
presentation. This particular annotation reflects the source?s importance as a resource
filled with general and detailed statics discussing the disparities of Alzheimer?s disease.
This source has changed the way I perceive the social and socioeconomic scope of the
disease.
Karlawish, J. (2011, October 14). Addressing the ethical, policy, and social challenges of
Preclinical Alzheimer disease. Neurology, 77(15), 1487-1493.
doi:10.1212/wnl.0b013e318232ac1a
Roberts, J. S., Mclaughlin, S. J., & Connell, C. M. (2014, October 01). Public beliefs and
Knowledge about risk and protective factors for Alzheimer's disease. Alzheimer's &
Dementia, 10(5), S381-S389. doi:10.1016/j.jalz.2013.07.001
In this journal article the researchers attempt to assess public beliefs and knowledge
surrounding the risk and protective factors for Alzheimer?s disease. A brief survey
module was used and added to the Health and Retirement Study, a longstanding national
panel study of the U.S. population over the age of 50. The researchers found a potential
interest in middle-aged adults and believe further education efforts are needed to address
misconceptions about risk and protective factors. As experienced researchers and
academics Roberts, McLaughlin, and Connell supported their experiment well with
existing scholarly research. They noted the contrasted in previous research on this subject
to more recent literature such as their own. Surveys and demographic data were used as
methods to come to their conclusions. The academic journal article is timely, reliable,
descriptive, well researched, and peer-reviewed. This source reflects views of older
adults and potential commonly held misconceptions about AD. I agree that examining a
broader range of illness perceptions would also be useful. The annotation shown above
helped explain public beliefs and my own misconception about AD risk and protective
factors.
Rolland, Y., Kan, G. A., & Vellas, B. (2008). Physical Activity and Alzheimer's Disease: From
Prevention to Therapeutic Perspectives. Journal of the American Medical Directors
In this journal article the authors discuss psychical activity for the prevention of
Alzheimer?s disease. The argument is made extensively for physical active and its
protective benefits on the brain functioning of elders. Physical activity may also slow Hershey 4 down the course of Alzheimer's disease. Epidemiological research is used to present
evidence for lifestyle factors such as inactivity, which may affect the progression of
Alzheimer?s disease. Their purpose is to review the literature concerning the correlation
between physical activity and its potential impact on the risk of Alzheimer's disease. This
review was conducted by identifying the relevant articles published between January
1966 and October 2007 using the following key words: Alzheimer, cognitive decline,
dementia, physical activity, and exercise. Case-control studies, randomized control trails,
basic research, and other epidemiological arguments were also reviewed. Researchers,
Rolland, Abellan van Kan, and Vellas concluded that regular physical activity is a key
component of successful aging. In addition increasing evidence suggests that an active
life has a protective effect on brain functioning in the elderly population. The academic
journal article is timely, reliable, descriptive, well researched, peer-reviewed, and has no
conflicts of interest.
Association, 9(6), 390-405. doi:10.1016/j.jamda.2008.02.007
Scheltens, P. (2016, July 30). Alzheimer's disease. The Lancet (British Edition), 388(10043),
505-517. doi:10.1016/S0140-6736(15)01124-1
In this journal article the authors discuss the main developments in Alzheimer?s research.
They argue that Alzheimer?s disease is the most prevalent cause of dementia, yet
researchers still use simple assumptions about the causality of the disease. Instead, the
researchers explore age-related, protective, and disease-promoting factors, which interact
with the core mechanisms of the disease. In the search for understanding the disease
mechanism and keys to treatment, research is moving more into the earliest phase of
Alzheimer?s disease. Eventually, they believe there will be a time in which specific antiAlzheimer?s therapies will combine with lifestyle interventions targeting general brain
health to jointly fight the disease. This will be achieved through development in rapidly
progressing research and technical breakthroughs.
As an experienced researchers, Scheltens, Blennow, Breteler, Strooper, Frisoni, Salloway,
and Van der Flier are aware the general background literature of Alzheimer?s disease.
They support their ideas that more attention should be paid to the onset of early
Alzheimer?s disease, rather then later stages. Clinical panels, related scholarly research,
epidemiological data, genetic research, biomarkers, imagining and scans are used to back
up their arguments. The academic journal article is timely, reliable, descriptive, well
researched, and peer-reviewed.
The annotation above both summarizes and assesses the scientific journal article in the
citation. The first paragraph provides a brief summary of the researchers objectives,
pertinent background knowledge, and a summary covering the main points of their work.
The second paragraph points out the projects strengths and evaluates its methods and
presentation. This particular annotation reflects the source?s importance as an article
filled with general and detailed information for a research paper on Alzheimer?s disease.
This source has changed the way I look at the various stages of the disease. Hershey
Thesis Statement
Alzheimer's Disease: Not Just Loss of Memory
Alzheimer's Disease: Not Just for the elderly
Diagnosis and Treatment of Alzheimer?s Disease: Current Challenges
THE CAUSES AND EFFECTS OF ALZHEIMER?S DISEASE: THE SILENT DISEASE
Use social health disparities thesis not scientific 5
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